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International Journal of

Recent Trends in Engineering

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International Journal of Recent Trends in Engineering (IJRTE)

ISSN 1797-9617

Volume 1,  Number 1,  May 2009

Issue on Computer Science

Page(s): 550-555

Metrics Based Accuracy Perpetuation for Bioinformatics Sequence Analysis Tools

           Jayanthi Manicassamy, and P. Dhavachelvan

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Abstract

Bioinformatics refers computational biology that merges with other fields of sciences like applied mathematics, statistics, chemistry for solving biological problems. The research areas in this field include sequence analysis, protein-protein interaction, gene expression analysis which leads it path in drug discovery, disease identification, and evolutionary relationships. At present the bioinformatics tools are increasingly important to allow real-time decision making for solving biological problems. Performance of a tool can be evaluated by means of feature, functionality comparison or by means of evaluating metrics. Metrics based evaluation leads to measure the qualities that qualify the characteristics of the product. In this work, some of the sequences analysis tools are considered for evaluating the accuracy of mining the required information’s with respect to the key characteristics like functional analysis, structural analysis, and similarity analysis. The selected bioinformatics sequence analysis tools that have been analyzed here have been evaluated by means of features, functionalities comparison and by means of evaluating metrics which has been represented in this paper. The performance evaluation is made with the use of selected metrics such as accuracy, sensitivity etc… with detailed result analysis. This result analyzed from the observation made on sequence analysis tools provides a standard guideline for developing and maintaining better systems with enhanced qualities.

Index Terms

Sequence Analysis, Bioinformatics, Performance Evaluation, Accuracy, Software Metrics

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